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Skinformed
Trendaka cica cream · tiger grass · madecassoside

Centella asiatica (cica)

Caution: Soothing-ish, barely studiedevidence: weak/contestedPEER-REVIEWED 2021

Centella (you'll see it sold as 'cica') is marketed as a soothing, barrier-calming hero. Reviews are cautiously positive, but nearly all the promising data comes from lab dishes and animals, with very few human trials, and those often test it blended with other ingredients so no one can say what the cica itself did. Almost certainly harmless. Just not the proven miracle the packaging suggests.

what the evidence says

Reviews credit Centella with soothing and barrier effects but note most evidence is in-vitro or animal, with sparse human trials and many combination products.

last reviewed 2026-07-03

sources

  1. 1.Evidence-Based Complementary and Alternative Medicine · Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms (2021)

note:Skinformed is general education, not medical advice. It doesn't know your skin, can't diagnose anything, and is no substitute for a clinician. If something on your skin hurts, spreads, or worries you, that's a doctor visit, not a product search.